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Shaw makes a distinction between genital behavior and sexual behavior. Mistaking one for the other, she says, leads to dishonesty and dissatisfaction.
Have you ever had vascular surgery or other treatments for your blood vessels?
Erectile dysfunction. A number of devices have been developed to ascertain the occurrence of an erection during sleep. This snap gauge is fastened around the penis but opens when an erection occurs.
Despite considerable recent experimentation in animal models and human volunteers, information on the central pathways of erection remains cursory at best.18 It is known that androgens play a predominantly modulating role by their effect on libido and sexual behaviour. Testosterone enhances sexual interest and the frequency of sexual acts; it increases the frequency of nocturnal erections but does not effect reflexogenic or psychogenic erections.19
PDE5 blockade not only increases intratumoral CD8+ infiltration and activation but also enhances their tumoricidal activity (Fig. 2). The ability to favorably alter the intratumoral microenvironment, thereby permitting tumor-specific T cells to directly interact with their targets, is critical for maximal antitumor immunity. Effective immunotherapy requires tumor-specific CTLs to infiltrate the tumor and kill their target in situ. Although no clinical advantage was derived by the presence of tumor-specific CTLs in the peripheral blood in melanoma patients (40), their frequency in the tumor correlated with a favorable prognosis (41). These clinical observations seem to be confirmed in our model where sildenafil treatment (a) increased the CD8+ T cell tumor infiltration (Fig. 4 B) and (b) increased the percentage of activated T cells (Fig. 4, C and D). Moreover, the number of tumor-infiltrating T cells directly correlated with a measurable antitumor effect (Fig. 3).
If the vasculature within the corpora cavernosa is healthy, the use of injectable agents is almost always effective. Patients need to be carefully instructed on how to perform the injections. The dosage is adjusted to achieve an erection with adequate rigidity for no more than 90 minutes. Up to 40 mcg of alprostadil can be used. An abnormal finding after biothesiometry testing has been suggested as an indicator of possible heightened sensitivity to intracavernosal injections, but this is unproven.
Healthfacts, March, 1999 by Maryann Napoli
Severe kidney failure requiring dialysis
is a staff urologist at Naval Hospital Jacksonville. Dr. Green is a graduate of the University of Texas Health Science Center at San Antonio and completed his residency at Naval Medical Center, Portsmouth, Va.
Bulbocavernosus reflex: This test evaluates nerve sensation in the penis. During the test, your doctor will squeeze the head of your penis, which should immediately cause your rectum to contract. If nerve function is abnormal, there will be a delay in response time or absence of rectal contraction.
Causes of Erectile Dysfunction: -
Out of 117 men who were suitable for taking sildenafil, the acceptance of sildenafil as a treatment option is high, 98.3% (115/117). Sildenafil was successful in treating ED in 91.3% (84/92) of this study population. At the end of the study period, 79.7% (59/74) of men wanted to continue treatment with sildenafil. The side effect profile of sildenafil in this study would appear to be different from previous published data  in that the incidence of headache, flushing, dyspepsia and abnormal vision is higher, but in the absence of a control group the significance of this is uncertain. It must be noted that 13% of men who reported side effects at Visit 2 reported complete lack of them at Visit 3. It is of interest that there is a 2% incidence each of thirst and 'dazed feeling' (reported by patients as a 'muzzy head'). The physiology underlying this is unclear, although it could be related to PDE inhibition in the brain, where the various PDE isoenzymes are in abundance .
rgery to repair arteries can reduce impotence caused by obstructions that block the flow of blood to the penis. The best candidates for such surgery are young men with discrete blockage of an artery because of a physical injury to the pubic area or a fracture of the pelvis. The procedure is less successful in older men with widespread blockage of arteries.
"There are several reasons ophthalmologists need to be acquainted with the pharmacologic profiles of PDE5 inhibitors and their potential side effects," the authors wrote "The frequency of erectile dysfunction, which is a form of peripheral vascular disease that impairs men's abilities to achieve and maintain an erection, increases dramatically with age and in the presence of cardiovascular risk factors. Therefore, many men who take PDE5 inhibitors to treat their erectile dysfunction will also be followed up by ophthalmologists for ocular disorders such as diabetic retinopathy, macular degeneration and ocular vascular disease."
Fatigue Brain or spinal-cord injuries
The end result: The couple can stop communicating altogether -- not only in the bedroom, but in all aspects of their relationship. And that, say experts, can only make problems worse for both partners.
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